1. Strength


2. Quantity

Prescription Required
IMPORTANT NOTE: A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.
Difference between Brand & Generic?

What is Nexium?

Nexium (esomeprazole) is a proton pump inhibitor (PPI) that is used to treat stomach acid and esophagus conditions such as gastroesophageal reflux disease (GERD). Nexium relieves symptoms including heartburn, persistent cough and difficulty swallowing by decreasing the amount of acid which is produced by the stomach.

Always read the medication information and instructions before using this medication.
Always follow your doctor’s directions.

  • Nexium should be taken an hour before a meal.
  • Take esomeprazole with a full glass of water.
  • Swallow Nexium whole without chewing or crushing tablets.
  • If you struggle to swallow Nexium whole, the contents of capsules may be sprinkled onto pudding or applesauce.
  • Take esomeprazole for the full amount of time prescribed even if your symptoms have improved.
  • Nexium is typically taken for between four and eight weeks. Your doctor may then recommend further treatment.
  • Tell your doctor if your conditions persist or worsen.


Make sure to tell your doctor:

  • If you have any drug or other allergies.
  • If you take any other prescription or over-the-counter medications.
  • Your medical history especially of liver disease, osteoporosis, autoimmune disease, systemic lupus, or low levels of magnesium in your blood.
  • If you are pregnant, planning on pregnancy or breastfeeding.

Other information you should also know:

  • Nexium may affect medical test results. Tell all of your medical care providers that you use this medication.
  • You may be more likely to break a bone if you take Nexium more than once a day or for an extended period of time.

Side Effects of Nexium

Common side effects of Nexium:

  • Abdominal pain.
  • Headache.

If you have any of the following esomeprazole side effects, seek medical help:

  • Persistent diarrhea, fever, abdominal pain or cramping or blood or mucus in your stool. Do not take anti-diarrhea or opioid medications if these symptoms occur.
  • Low magnesium level symptoms including seizures, persistent muscle spasms or an irregular, slow or fast heartbeat.
  • Lupus symptoms including a rash on the cheeks or nose or worsening joint pain.
  • Vitamin B-12 deficiency symptoms including weakness, sore tongue or a numbness in the hands or feet. The risk of this is increased if you have been taking esomeprazole or other proton pump inhibitor for 3 years or longer.
  • Symptoms of an allergic reaction including difficulty breathing, hives or swelling in your face, lips or throat.


What should I do if I miss a dose of Nexium?

If you miss a dose of Nexium, you should take it as soon as you remember. However, if it is almost time for your next dose, then skip your missed dose.

What is the generic alternative to Nexium?

Generic Nexium is known as esomeprazole and is available in 20mg and 40mg strengths.

A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

Your Lowest Price, Guaranteed

Our goal is to bring you the most affordable medication. If you find a lower price advertised by another website or your local pharmacy, we’ll match that price or beat it by 10% of the difference.* Call us at 1-877-204-1509 and a member of our CareTeam will be happy to assist you.

Call 1-877-204-1509
* Some exceptions may apply
Some exceptions may apply. To qualify for price matching, competitors must meet our standards for patient safety. Advertised prices must be for medication of the same type, strength, quantity, and form.

Real Customers, Honest Reviews

The last order came in a timely fashion and like all others, service has been without any problems. Keep up the excellent work.
Harold August 30, 2021

Real Customers, Honest Reviews

The medication to treated SIBO in the USA is absolutely over priced as it has to be used usually twice a year. True Canada Pharmacy helped me obtain 2+ treatment doses of it for far, far, far less than 1 treatment dose cost in the USA. Due to the pandemic it takes a while to get it but we are all set for the next time it recurs. Thank you so very much.
Cryss August 30, 2021

Real Customers, Honest Reviews

Very easy to refill. Quick delivery
Pam August 30, 2021

Real Customers, Honest Reviews

I was frustrated with the Visa payment system being inoperable, but I have to say that when they went ahead a filled the Rx and said they would process the claim when it went back up, that was exceptional service - thank you
Christopher July 27, 2021

Real Customers, Honest Reviews

Your representative are very thorough, knowledgeable, and helpful.
Randy July 27, 2021

Real Customers, Honest Reviews

Always friendly and helpful. Product arrived in a timely manner. Was kept up to date on the process on the mailing process
Rita July 27, 2021

Real Customers, Honest Reviews

I very much appreciate the reminders and efficiency of the staff.
Monica July 26, 2021

Real Customers, Honest Reviews

We have been very happy with the service.
Mary July 26, 2021

Real Customers, Honest Reviews

I have used Canadian Pharmacy for at least 10-12 years. I have been very grateful to be able to get my life saving scripts at reasonable affordable prices. The follow-up of your Reps is excellent. During the COVID 19 virus outbreak scripts took much longer to receive. I think thus was partly due to the U.S.P.S. assault by DeJoy as Postmaster General. Before COVID 19 it took approx. 2-3 weeks to receive meds; during COVID 19 and the US General Election year, it took easily 2 months to receive scripts. It will be interesting to see if future orders arrive any more quickly after DeJoy is no longer Postmaster General?!
Jennifer June 9, 2021

Real Customers, Honest Reviews

Good experience. I found another pharmacy with a lower price than yours, and you did lower the price for me. It took some time to get everything straight, so you expedited the mail and I received it on time. Thank you.
Linda May 25, 2021
Read All Reviews
Write a Review

Get our newsletter

Health news and medication updates delivered right to your inbox.