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Asacol (mesalamine) is an ulcerative colitis medication which is used to reduce symptoms such as stomach pain, diarrhea and rectal bleeding. Mesalamine decreases swelling within the colon and prevents your body from producing natural substances which may cause inflammation.

Always read the medication information and instructions before using this medication.
Always follow your doctor’s directions.

• Asacol should be taken on an empty stomach one hour before or two hours after a meal.
• Swallow Asacol whole with a full glass of water and without chewing or crushing.
• Take mesalamine for the full amount of time prescribed, even if you begin to feel better and your symptoms clear.
• Do not stop taking mesalamine without speaking to your doctor.
• Talk to your doctor if your condition persists or if you find undissolved tablets in your stool.

Make sure to tell your doctor:

• If you have any drug or other allergies.
• If you take any other prescription or over-the-counter medications.
• Your medical history especially of liver disease, kidney disease, heart disease, pyloric stenosis or a history of blockage in your intestinal tract or stomach.
• If you are pregnant or planning pregnancy.
• If you are breast-feeding.

Other information you should also know:

• Asacol can cause unusual medical test results. Tell all of your doctors or any medical testing personnel that you take mesalamine.

Common side effects of Asacol:

• Headaches.
• Muscle or joint pain.
• Nausea or vomiting.
• Constipation.
• Stomach upset.
• Whole or partial tablets in your stool. Tell your doctor if this occurs regularly.

If you have any of the following mesalamine side effects, seek medical help:

• Worsening symptoms of ulcerative colitis including increased abdominal pain, cramping, fever or bloody diarrhea.
• Persistent nausea or vomiting.
• Severe stomach or abdominal pain.
• Jaundice.
• Chest pain or shortness of breath.
• Dark urine.
• Symptoms of a kidney problem such as a change in your amount of urine.
• Symptoms of an allergic reaction including difficulty breathing, hives or swelling in your face, lips or throat.

What should I do if I miss a dose of Asacol?

If you miss a dose of Asacol, you should take it as soon as you remember. However, if it is almost time for your next dose, then skip your missed dose.

What is the generic alternative of Asacol?

Generic Asacol is known as mesalamine and is available in the same 400mg and 800mg strengths.